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Hartmut H Malluche Selected Research

activin receptor type II-A (activin A receptor, type II)

1/2018The activin receptor is stimulated in the skeleton, vasculature, heart, and kidney during chronic kidney disease.
1/2017Ligand trap of the activin receptor type IIA inhibits osteoclast stimulation of bone remodeling in diabetic mice with chronic kidney disease.

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Hartmut H Malluche Research Topics

Disease

11Chronic Renal Insufficiency
01/2022 - 11/2007
11Bone Diseases (Bone Disease)
01/2020 - 06/2000
10Vascular Calcification
01/2022 - 03/2004
9Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets)
11/2019 - 06/2000
6Renal Insufficiency (Renal Failure)
03/2011 - 01/2002
5Hyperphosphatemia
01/2018 - 08/2002
5Hyperparathyroidism
01/2018 - 01/2002
5Chronic Kidney Failure (Chronic Renal Failure)
01/2015 - 01/2002
4Secondary Hyperparathyroidism
11/2019 - 08/2002
3Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 01/2010
3Kidney Diseases (Kidney Disease)
11/2019 - 03/2004
3Bone Resorption
01/2018 - 03/2008
3Hypercalcemia (Milk Alkali Syndrome)
11/2008 - 06/2002
2Osteoporosis
11/2021 - 10/2015
2Osteomalacia
03/2004 - 06/2000
1Atherosclerosis
01/2022
1Bone Fractures (Bone Fracture)
11/2021
1Cardiomegaly (Heart Hypertrophy)
01/2018
1Hereditary Nephritis (Alport Syndrome)
01/2018
1Fibrosis (Cirrhosis)
01/2018
1Frailty
01/2017
1Metabolic Bone Diseases (Osteopenia)
12/2015
1Premature Aging
12/2015
1Coronary Artery Disease (Coronary Atherosclerosis)
10/2015
1DiGeorge Syndrome (Syndrome, DiGeorge)
06/2014
1Uremia
03/2011
1Osteoarthritis
03/2008
1Diabetes Mellitus
03/2004

Drug/Important Bio-Agent (IBA)

10Parathyroid Hormone (Parathormone)IBA
07/2016 - 01/2002
8MineralsIBA
01/2022 - 08/2002
6Calcitriol (Calcijex)FDA LinkGeneric
11/2008 - 01/2002
5CalciumIBA
11/2019 - 03/2004
5Phosphates (Orthophosphate)IBA
01/2015 - 03/2004
5Vitamin DFDA LinkGeneric
11/2008 - 01/2002
3Fibroblast Growth Factor-23IBA
01/2022 - 01/2015
3Phosphorus (Red Phosphorus)IBA
07/2016 - 03/2004
3AdenineFDA LinkGeneric
01/2015 - 03/2009
3Hormones (Hormone)IBA
08/2002 - 01/2002
2Diphosphonates (Bisphosphonates)IBA
11/2021 - 03/2009
2Biomarkers (Surrogate Marker)IBA
01/2020 - 05/2010
2ActRIIA-mIgG2aFc fusion proteinIBA
01/2018 - 01/2017
2activin receptor type II-A (activin A receptor, type II)IBA
01/2018 - 01/2017
2LigandsIBA
01/2018 - 01/2017
2Sevelamer (RenaGel)FDA Link
01/2015 - 02/2008
2AluminumIBA
03/2004 - 01/2002
1ACE-011IBA
11/2019
1Hemoglobins (Hemoglobin)IBA
11/2019
1Proteins (Proteins, Gene)FDA Link
11/2019
1Fibronectins (Fibronectin)IBA
01/2018
1Activin Receptors (Activin Receptor)IBA
01/2018
1activin AIBA
01/2017
1salicylhydroxamic acid (SHAM)IBA
01/2017
1OsteoprotegerinIBA
12/2015
1SirtuinsIBA
12/2015
1ChromatinIBA
12/2015
1sucroferric oxyhydroxideIBA
01/2015
1IronIBA
01/2015
1lanthanum carbonate (Fosrenol)FDA Link
01/2015
1Ribonuclease III (RNase III)IBA
06/2014
1EnzymesIBA
06/2014
1diphosphoric acid (pyrophosphoric acid)IBA
03/2011
1Durapatite (Hydroxylapatite)IBA
03/2009
1Calcifediol (Calcidiol)FDA Link
11/2008
1Collagen Type II (Type II Collagen)IBA
03/2008
1CollagenIBA
03/2008
1Calcium Carbonate (Limestone)FDA Link
02/2008
1paricalcitol (Zemplar)FDA Link
11/2007
1carboxyl-terminal parathyroid hormoneIBA
11/2007
1Biological ProductsIBA
08/2002
11,25-dihydroxyvitamin DIBA
01/2002

Therapy/Procedure

6Therapeutics
03/2012 - 01/2002
4Kidney Transplantation
01/2022 - 06/2000
4Renal Dialysis (Hemodialysis)
01/2017 - 02/2008
3Oral Administration
11/2008 - 01/2002
2Transplantation
01/2010 - 06/2000
1Duration of Therapy
11/2021
1Parathyroidectomy
11/2019
1Injections
03/2011
1Continuous Ambulatory Peritoneal Dialysis (CAPD)
03/2004